HTRIdb (https://www.lbbc.ibb.unesp.br/htri/) is a database of literature curated human TF-target interactions. As the database is recently offline, the data is distributed by the OmniPath rescued data repository (https://rescued.omnipathdb.org/).
Examples
htridb_data <- htridb_download()
#> New names:
#> • `` -> `...8`
htridb_data
#> # A tibble: 18,630 × 8
#> OID GENEID_TF SYMBOL_TF GENEID_TG SYMBOL_TG TECHNIQUE PUBMED_ID ...8
#> <dbl> <dbl> <chr> <dbl> <chr> <chr> <dbl> <lgl>
#> 1 32399 142 PARP1 675 BRCA2 Electrophoreti… 18990703 NA
#> 2 32399 142 PARP1 675 BRCA2 Chromatin Immu… 18990703 NA
#> 3 28907 196 AHR 1543 CYP1A1 Chromatin Immu… 16972788 NA
#> 4 29466 196 AHR 1543 CYP1A1 Electrophoreti… 10359656 NA
#> 5 28911 196 AHR 1543 CYP1A1 Chromatin Immu… 17785579 NA
#> 6 34590 196 AHR 1543 CYP1A1 Electrophoreti… 9698073 NA
#> 7 34466 196 AHR 1544 CYP1A2 Chromatin Immu… 17785579 NA
#> 8 34467 196 AHR 1545 CYP1B1 Chromatin Immu… 17785579 NA
#> 9 34485 196 AHR 1545 CYP1B1 Electrophoreti… 12801909 NA
#> 10 34470 196 AHR 2353 FOS Electrophoreti… 10478842 NA
#> # ℹ 18,620 more rows
# # A tibble: 18,630 x 7
# OID GENEID_TF SYMBOL_TF GENEID_TG SYMBOL_TG TECHNIQUE
# <dbl> <dbl> <chr> <dbl> <chr> <chr>
# 1 32399 142 PARP1 675 BRCA2 Electrophoretic Mobi.
# 2 32399 142 PARP1 675 BRCA2 Chromatin Immunoprec.
# 3 28907 196 AHR 1543 CYP1A1 Chromatin Immunoprec.
# 4 29466 196 AHR 1543 CYP1A1 Electrophoretic Mobi.
# 5 28911 196 AHR 1543 CYP1A1 Chromatin Immunoprec.
# # . with 18,620 more rows, and 1 more variable: PUBMED_ID <chr>