Skip to contents

Downloads TF-target interactions from TRRUST

Source: R/trrust.R
trrust_download.Rd

TRRUST v2 (https://www.grnpedia.org/trrust/) is a database of literature mined TF-target interactions for human and mouse.

Usage

trrust_download(organism = "human")

Arguments

organism

Character: either "human" or "mouse".

Value

A data frame of TF-target interactions.

Examples

trrust_interactions <- trrust_download()
trrust_interactions
#> # A tibble: 11,698 × 4
#>    source_genesymbol target_genesymbol effect reference
#>    <chr>             <chr>              <dbl> <chr>    
#>  1 AATF              BAX                   -1 22909821 
#>  2 AATF              CDKN1A                 0 17157788 
#>  3 AATF              KLK3                   0 23146908 
#>  4 AATF              MYC                    1 20549547 
#>  5 AATF              TP53                   0 17157788 
#>  6 ABL1              BAX                    1 11753601 
#>  7 ABL1              BCL2                  -1 11753601 
#>  8 ABL1              BCL6                  -1 15509806 
#>  9 ABL1              CCND2                  1 15509806 
#> 10 ABL1              CDKN1A                 1 11753601 
#> # ℹ 11,688 more rows
# # A tibble: 11,698 x 4
#    source_genesymbol target_genesymbol effect reference
#    <chr>             <chr>              <dbl> <chr>
#  1 AATF              BAX                   -1 22909821
#  2 AATF              CDKN1A                 0 17157788
#  3 AATF              KLK3                   0 23146908
#  4 AATF              MYC                    1 20549547
#  5 AATF              TP53                   0 17157788
#  6 ABL1              BAX                    1 11753601
#  7 ABL1              BCL2                  -1 11753601
# # . with 11,688 more rows