Builds a gene regulatory network using data from the ReMap database and converts it to a format suitable for NicheNet.

## Usage

nichenet_gr_network_remap(
score = 100,
top_targets = 500,
only_known_tfs = TRUE
)

## Arguments

score

Numeric: a minimum score between 0 and 1000, records with lower scores will be excluded. If NULL no filtering performed.

top_targets

Numeric: the number of top scoring targets for each TF. Essentially the maximum number of targets per TF. If NULL the number of targets is not restricted.

only_known_tfs

Logical: whether to exclude TFs which are not in TF census.

## Value

Data frame with gene regulatory interactions in NicheNet format.

• remap_filtered
• nichenet_gr_network
if (FALSE) {